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Pustular Psoriasis

Question:

What were your signs and symptoms of pustular psoriasis? Submit Your Comment

Comment from: mspsoriasisgirl, 35-44 Female (Patient) Published: February 03

Back in 2003 I went in for surgery and 4 days later I developed a patch of pustules and a rash-looking area, and they sent me home with a hydrocortisone cream. Within one week's time I was covered in pustules over 95 percent of my body. I was admitted to the hospital where they believed it was Stevens-Johnson syndrome until they took skin biopsies and it showed that it was pustular psoriasis caused by the lithium I was on. I spent 62 days in the local hospital and 21 days on a burn unit. I had a 1 year old baby and could not see her due to risk of infection. They told my husband I was dying. Twelve years later and I haven't had a flare like that since, but now I have a flare that most won't talk about; it's all over my genitals! Gross! Anyway, the first doctor thought it was herpes so I got a second opinion and they skin tested it and did an STD test and lo and behold the first doctor was wrong, it was pustular psoriasis rearing its ugly head once again. It will get better but right now I feel like my genitals were shredded by a cheese grater. So be aware all that it can happen to all areas of the body.

Comment from: Cherry, 65-74 Female (Patient) Published: February 23

I got pustular psoriasis 1 week before surgery. Dermatologist said it was stress and would go away. I was 45, I am now 72 and still have it. I have been through so many treatments, even Laser, and I even have a UVB machine. The only thing that helps is soaking feet and hands in warm water, then applying only Vaseline, and putting my socks on after. I cannot wear gloves all the time. Washing my hands constantly helps also. Stress seems to be the biggest factor for a flare up. Hope this helps some of you.

Comment from: Nika0918, 45-54 Female (Patient) Published: January 13

I was diagnosed with pustular psoriasis when I was in my late twenties. I remember when I was first diagnosed. I was constantly breaking out on my palms and the instep of my foot. I tried a bunch of topical creams (that didn't work) but the things that did work the best for me was sunlight, salt water and managing stress. It is difficult to show those areas during break outs but it is important to do it. I found the more I stressed about the psoriasis, the worse it got - I accepted that the condition was never going to go away and it seemed to get better on its own. I still breakout on my feet but not as badly.

Comment from: Tonya, 35-44 Female (Patient) Published: October 14

I was diagnosed with pustular psoriasis about three years ago. I've been on Humira, Stelara, Soriatane, Remicade, and methotrexate. So far my psoriasis has just about crippled me with this last flare up that has lasted so far three weeks and counting. I can barely walk or stand the blisters now look like lesions that fill up with a yellowish to almost green pus that is excruciating to touch on my hands and both feet. It feels like I'm walking on a bunch of boils. They smell really bad and when I do actually get to bust them they fill right back up and all the pain is still there.

Comment from: inpain, 19-24 Female (Patient) Published: April 30

Four years ago I went to my doctor, who had said it was dermatitis, and had given me antibiotics and creams. I constantly went back in pain. I went again on Monday, as all my skin on fingers had blistered up and ripped off. I saw a new doctor who said it's not dermatitis, but pustular psoriasis. The creams she has given me aren't strong enough, nor are the antibiotics working. Now I'm worried as I don't know much about what I've got. Hopefully I will get fixed so I can carry on with my life and be a happy outgoing fun mother to my three young kids. I'm only 23!

Comment from: bmbranno, 55-64 Female (Patient) Published: December 24

My first outbreak of pustules on the palms of my hands was when I was producing a film for my first time ever and was near a nervous breakdown due to stress. I went to the hospital and they didn't have a clue what the condition was. Finally the pustules ceased on my palms but broke out on the bottoms of my feet. Since then a severe psoriasis has spread up my legs and affected my finger joints. I have horrible itching on the soles of my feet, my palms, and my legs. So far nothing the dermatologist has prescribed has worked. The condition seems to keep spreading. At least I now know what the condition is which even the dermatologist failed to diagnose properly.

Comment from: SIS, 75 or over Female (Patient) Published: September 10

I had very severe pustular psoriasis for two years. A Mayo Clinic biopsy diagnosed it. I took chemo drugs by mouth instead of injections. After two years of that it finally went into remission. I had one flareup that did not last long as it was treated immediately. Methotrexate was my salvation. It started as a scaley skin problem. What happens is we grow too many skin cells. That's why they scale. However I have been in remission for years now and am very happy. I was wearing white gloves all the time when it was active.

Comment from: audinga, 25-34 Female (Patient) Published: September 10

I was diagnosed with pustular psoriasis five months ago. It started with a small pustule on my palm. Kind of almost looked like a small whitehead. It got extremely worse and spread all over my palms, fingertips, heels and toes. The psoriasis spread to my fingernails where the nail has separated from the nail bed. Luckily, only one nail has fallen off, but I have four others that aren't looking too good. I have been prescribed several topical creams and have self medicated by going to the tanning bed (UVB therapy). I was also told I will probably develop psoriatic arthritis. The next option is to start the Humira injections. I am hoping to get some relief from this medicine.

Comment from: lifewasfun, 75 or over Female (Patient) Published: July 31

I had these blisters appear on the palm of my hands about 6 months ago. As I had a regular appointment with my doctor, I ask about them, was told it was pustular psoriasis and she prescribed a cream called Clobetasol Propionate 0.05%. I'm not sure it is doing anything. My feet have now broken out, soles of the feet & heels. My knees and elbows are showing signs now. It is very painful to walk and my hands itch all the time. I am looking at these sites hoping to learn more.

Comment from: angstandvexed, 25-34 Female (Patient) Published: April 30

I have had pustular psoriasis for about 3 years now. I am taking Enbrel and Prednisone for it, and had it under control (but no exceptional clearing). Recently I started using Burts Bee's products, washing the area in Witch Hazel, and using Miracle of Aloe Psoriasis Cream. The psoriasis has not gone away, but it has gotten a lot better.

Comment from: Joy, 55-64 Female (Patient) Published: January 24

I have just been told I have pustular psoriasis and this has been very helpful for me in understanding what is going on with my hands.

Comment from: Misty, 55-64 Female (Patient) Published: January 06

I was diagnosed with pustular psoriasis six years ago. I have it on my hands, feet, head and sometimes my legs. Nothing has helped me so far from the doctor. I have been using a new cream called Aveeno Eczema therapy. It has really helped the itching and dry skin. I am also taking sea salt, oatmeal, Epsom salt baths every other night and it has kept the blisters away so far. I have only been doing this a week. I have developed numbness on the left side of my face, both inside and out and on my chin. The doctor thinks I may have MS. I am wondering if the pustular psoriasis has caused this, if I do have MS. I am so scared.

Comment from: tiredofit, 45-54 Female (Patient) Published: December 13

I have chronic pustular psoriasis on palms and soles of feet. I have now been diagnosed with lichen sclerosis which is quite similar but located on different part of body. Most of treatments have too adverse side effects for me to want to attempt.

Comment from: hodge , 19-24 Female (Caregiver) Published: November 09

My 19 year old daughter has spent 6 weeks in UNC Hospital in Chapel Hill with horrid effects of pustular psoriasis. Her child was delivered 2 months early just to save her life. It has now been 2 months since the delivery and her symptoms have not subsided. She had to shave her head due to the sores and loss of hair. She can't even hold her sweet baby that is now out of NICU and we are at wits end. Her pain is severe, her fever up and down. The sores alone, I fear for the long term scaring.

Comment from: bad feet, 55-64 Female (Patient) Published: October 31

I have had pustular psoriasis now for almost 20 years. It started on my hands. That disappeared and then came on my feet. I feet itch and burn so bad and I can hardly walk sometimes. I can go to bed with clear feet and wake up with hundreds of little pus blisters the next morning. Nothing helps. Have spent hundreds of dollars on meds and even had light treatment 3 times a week but to no avail...

Comment from: Dee Dee, 55-64 Female (Patient) Published: June 08

I have it on the palms of both hands. The first severe attack came 10 years ago. I felt fine and all of a sudden I could not walk. Then I noticed my palms were broken out. I could not go to work for 3 weeks. I went to some specialists, but no one diagnosed it. I have had minor flare ups with no great pain until now. A month ago I had severe pain in my chest and shoulder accompanied by a severe flare-up. I have a new doctor, and she took a sample of the pustule. I just got the lab report back, so now my doctor and I will have to decide where to go with this.

Comment from: Regina, 45-54 Female (Patient) Published: June 01

I was diagnosed with pustular psoriasis nearly 6 years ago. It started on my right palm as 2 blisters, now I am almost constantly in a "flare." My palms and soles are both involved, including the sides of my heels and toes, which makes it very difficult and painful to walk. I have had one or two pustules on my arms, back of my hands and on my head. I have tried many things over the years to keep it at bay, including PUVA therapy. Nothing has worked.

Comment from: 45-54 Female (Patient) Published: May 19

My symptoms of pustular psoriasis include: fevers, nausea, bad headaches, lethargy, facial swelling, large areas of pustule formation on my face, and inside my nose and mouth! This can go on for months at a time. I also have psoriatic arthritis.

Comment from: alpesh, 35-44 Male (Patient) Published: April 28

With my pustular psoriasis, I have reddening of palms of my hands. The skin is becoming thick on my hands, which are itching profusely, and my skin is coming off in layers.

Comment from: greta5, 45-54 Female (Patient) Published: April 06

I have pustular psoriasis on my hands and feet. Mine comes and goes in cycles. It will be better for a couple of weeks, and then it returns. I have been struggling with this for almost two years now.

Comment from: Rae, 45-54 Female (Patient) Published: April 04

I have pustular psoriasis on the heel of my left foot. It was so bad I felt like I was walking on needles. My foot doctor gave me a special boot that has the heel cut out. I am on my feet all day at work and I find this helps when it gets bad.

Comment from: pauls mom, 45-54 Female (Patient) Published: April 01

I also have pustular psoriasis on the feet and hands. It is all over my heels sides and bottoms of my feet. It is difficult to walk. This is very painful. I am currently taking Humira, but it continues to spread to other areas of my feet.

Comment from: flo, 55-64 Female (Patient) Published: February 22

I have pustular psoriasis on the palms of my hands and sides and heels of my feet. Nothing I try helps, and my skin on my feet get deep cracks and it is painful to walk.

Comment from: Lane, 45-54 Female (Patient) Published: July 06

I have ar psoriasis on both palms and both feet... Started on hands about 10 years ago, intense itching & burning. Occurring more frequently now. Became worse on feet, very painful to walk or stand. Diagnosed two years ago.

REFERENCES:

Levin, Ethan C., et al. "Biologic Therapy in Erythodermic and Pustular Psoriasis." Journal of Drugs in Dermatology 13.3 March 2014: 342-354.

Posso-De Los Rios, Claudia J., et al. "A Systemic Review of Systemic Medications for Pustular Psoriasis in Pediatrics." Pediatric Dermatology (2014): 1-10.

Robinson, A., et al. "Treatment of pustular psoriasis: from the Medical Board of the National Psoriasis Foundation." J Am Acad Dermatol 67.2 Aug. 2012: 279-288.

Umezawa, Y., et al. "Therapeutic Guidelines for the Treatment of Generalized Pustular Psoriasis (GPP) Based on a Proposed Classification of Disease Severity." Arch Dermatol Res 295 (2003): S43-S54.

Viguier, M., et al. "Efficacy and safety of tumor necrosis factor inhibitors in acute generalized pustular psoriasis." Arch Dermatol 148.12 Dec. 2012: 1423-1425.

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