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DVT (Blood Clot in the Leg)

Question:

What medications were effective in treating DVT? Submit Your Comment

Comment from: Survivor, 55-64 Female (Patient) Published: October 04

I have had 2 episodes of DVT (deep vein thrombosis) on my left leg. Once, when I was in my twenties. The second, when I was in my thirties during my 9th week pregnancy. I was hospitalized for 20 days. I had to have heparin jabs 3 times a day during my stay in the hospital. After I was discharged, I had to continue to jab Fraxiparine once a day until I gave birth. I also had to continue the jab for a week after giving birth. Since then, I never had any occurrence and I am now in my early sixties.

Comment from: Francesca, 45-54 Female (Patient) Published: May 31

Coumadin has always been the gold standard for treating blood clots. When pregnant, you cannot take Coumadin, instead, I took heparin injections. Not fun, but it worked. I few years back, my hematologist switched me to Xarelto. I had severe muscle cramps within thirty days, but fortunately those subsided. Unfortunately, I had a severe nosebleed that last over several hours and I was admitted to the hospital. I almost bled to death, and near the end of the saga I developed deep vein thrombosis 4. For me, Coumadin is the safest course of action. Even today, when my blood is not appropriately thinned (bit of a misnomer; it is not thin just less sticky and therefore less prone to clotting), I must also take heparin injections until my blood work (INR = International Normalized Ratio) is back to within a normal safe range. I will require anticoagulants for the balance of my life due to a rare blood clotting disorder known as antiphospholipid antibody syndrome.

REFERENCES:

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<https://www.uptodate.com/contents/approach-to-the-diagnosis-and-therapy-of-lower-extremity-deep-vein-thrombosis>

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<http://www.accessdata.fda.gov/drugsatfda_docs/label/2015/206316lbl.pdf>

FDA Prescribing Information. ARIXTRA® (fondaparinux sodium) infection.
<http://www.accessdata.fda.gov/drugsatfda_docs/label/2005/021345s010lbl.pdf>

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MedlinePlus. Deep Vein Thrombosis. Thompson, B.T., MD. "Overview of acute pulmonary embolism in adults." Updated: Aug 08, 2016.
<http://www.uptodate.com/contents/overview-of-acute-pulmonary-embolism-in-adults>

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